Email Spam Filtering: A Systematic Review surveys current and proposed spam filtering techniques with particular emphasis on how well they work. The primary focus is on spam filtering in email, while similarities and differences with spam filtering in other communication and storage media - such as instant messaging and the Web - are addressed peripherally. Email Spam Filtering: A Systematic Review examines the definition of spam, the user's information requirements and the role of the spam filter as one component of a large and complex information universe. Well known methods are detailed sufficiently to make the exposition self-contained; however, the focus is on considerations unique to spam. Comparisons, wherever possible, use common evaluation measures and control for differences in experimental setup. Such comparisons are not easy, as benchmarks, measures and methods for evaluating spam filters are still evolving. The author surveys these efforts, their results and their limitations.In spite of recent advances in evaluation methodology, many uncertainties (including widely held but unsubstantiated beliefs) remain as to the effectiveness of spam filtering techniques and as to the validity of spam filter evaluation methods. Email Spam Filtering: A Systematic Review outlines several uncertainties and proposes experimental methods to address them. Email Spam Filtering: A Systematic Review is a highly recommended read for anyone conducting research in the area or charged with controlling spam in a corporate environment.
The early, organ-specific diagnosis of malignancy continues to be a major unmet medical need. Clearly the ability to establish an early diagnosis of cancer is dependent upon an intimate knowledge of the cancer's biology, which if understood at the molecular level should identify key diagnostic and therapeutic manipulation points. Advances in recombinant gene technology have provided significant understanding of the mechanisms of action of oncogenic viruses, as well as of cancer-associated genomic sequences (onco genes). This text will explore the known molecular genetic, biolog ical, and clinical knowledge of selected human neoplasms that demonstrate association with suspected oncogenic virus and those cytogenetic alterations that either cause or are caused by oncogene activation. The text first reviews the cytogenetics of human cancers link ing classical cytogenetics and molecular genetics. Avery A. Sand berg (Roswell Park Memorial Institute, Buffalo, New York) reviews the leukemias and lymphomas, followed by S. Pathak (M. D. Anderson Hospital and Tumor Institute, Houston, Texas), who reviews solid tumors. Functional consideration of oncogenes is highlighted by Keith C. Robbins and Stuart A. Aaronson (NO, Bethesda, Maryland) through their description of the v-sis locus sis and its gene product p.28 ; a protein that closely resembles human platelet-derived growth factor (PDGF).
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